The patients were randomly assigned to receive extended-release niacin (target dose, mg per day) or ezetimibe (10 mg per day). The primary end point was the between-group difference in the change from baseline in the mean common carotid intima–media thickness after N Engl J Med. Nov 26;(22) doi: /NEJMoa Epub Nov Extended-release niacin or ezetimibe and carotid intima-media thickness. Taylor AJ(1), Villines TC, Stanek EJ, Devine PJ, Griffen L, Miller M, Weissman NJ, Turco M. Author information: (1)Cardiology Service, Walter Reed.
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27%. Simvastatin compared to simvastatin + ezetimibe for reduction in intima-media thickness (plaque growth) of the carotid-artery wall: patients with familial hyperlipidemia were included in this study. patients received simvastatin only and received simvastatin plus ezetimibe for two years. Simvastatin + ZETIA. By a margin of mm in carotid intima-media thickness (CIMT), extended-release niacin (Niaspan) demonstrated superiority over ezetimibe (Zetia) as an add-on for high risk patients on long term statin therapy.
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The outcome on carotid intima-media forgetfulness from ezetimibe and simvastatin vs simvastatin alone is bad. The zetia intimal thickness of the carotid arteries, also known as zetia intimal thickness intima-media anticipation or cIMT, is a history of risk for personal disease. The preliminary results from the Brand trial raised several questions, some of which carry the relationship of cIMT to LDL storage levels and the role of cIMT in.
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