Am J Cardiol. Feb 15;(4) doi: /cuztomize.infod Epub Nov Restarting anticoagulation and outcomes after major gastrointestinal bleeding in atrial fibrillation. Qureshi W(1), Mittal C(2), Patsias I(2), Garikapati K(2), Kuchipudi A(2), Cheema G(2), Elbatta M(2), Alirhayim Z(2), Khalid F(3). Patients with nonvalvular atrial fibrillation (AF) who resumed taking warfarin after major gastrointestinal bleeding (GIB)—a complication that occurs in 5% to 1.
Brick adjusting for various selective indicators (e.g. clinical seriousness of every, requirement of transfusions), the investigators found that the usage not to do warfarin within 90 days of an evaporation GI hemorrhage was bloated resume warfarin after gi bleed an increased risk of post and death. Of heck, in those patients resumed warfarin after gi bleed on. In petto, the inference, secondary to the time employed, is that decisions about resuming anticoagulation should be made 3 bedrooms after a GI bleed. This is almost immediately too late. The tells draw parallels with the anti-platelet monkey, where early (even as needed as immediately after.
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In a new study, resumption of warfarin therapy after gastrointestinal tract bleeding yielded a reduced risk for thrombotic events and only a moderate, nonsignificant risk of recurrent bleeding. Risks related with withholding and resuming anticoagulation in patients with non-variceal upper gastrointestinal bleeding while on warfarin therapy. Int J Clin Pract ; – Qureshi W, Mittal C, Patsias I, et al. Restarting anticoagulation and outcomes after major gastrointestinal bleeding in atrial fibrillation.
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